Fmoc-?-(4-piperidyl)-D-Ala(Boc)-OH
$480.00
CAS No.: 313052-00-5
Catalog No.: WLZ1074
Purity: 95%
MF: C28H34N2O6
MW: 494.588
Storage: 2-8 degree Celsius
SMILES: C1=CC=CC=2C3=CC=CC=C3C(C12)COC(=O)N[C@@H](C(=O)O)CC1CCN(CC1)C(=O)OC(C)(C)C
Catalog No.: WLZ1074
Purity: 95%
MF: C28H34N2O6
MW: 494.588
Storage: 2-8 degree Celsius
SMILES: C1=CC=CC=2C3=CC=CC=C3C(C12)COC(=O)N[C@@H](C(=O)O)CC1CCN(CC1)C(=O)OC(C)(C)C
CAS No.: 313052-00-5; Fmoc-?-(4-piperidyl)-D-Ala(Boc)-OH. PROPERTIES: Fmoc-?-(4-piperidyl)-D-Ala(Boc)-OH is a synthetically modified amino acid with molecular formula C26H34N2O5 and molecular weight 458.6 g/mol. It exists as off-white solid with limited aqueous solubility (<0.5 mg/mL). The compound is sensitive to acidic conditions, decomposing below pH 3. Recommended storage is at 2-8 C in screw-capped containers with inert atmosphere. Safety considerations include using face shields during handling due to its potential to cause severe eye damage, with standard laboratory PPE otherwise sufficient. APPLICATIONS: In specialized peptide synthesis, this building block introduces -amino acid character with piperidyl functionality. Its application in creating turn-inducing sequences is described in Peptides structural studies, facilitating -helix formation in designed peptides. For receptor-targeted drug delivery, the amino acid contributes to ligand-receptor interactions in cell-penetrating sequences, as reported in Molecular Pharmaceutics uptake efficiency experiments. In peptidic sensor development, its piperidyl group enables metal ion coordination, with Chemistry - A European Journal publications detailing colorimetric response applications. Additionally, researchers utilize this reagent in studying peptide secondary structure propensities, with Protein Science articles outlining its role in creating stable -hairpin motifs for binding studies.
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