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1-(1-ethyl-6-methyl-1H-benzo[d]imidazol-2-yl)-2,2,2-trifluoro-1-phenylethan-1-ol
$360.00
CAS No.: 2567984-61-4
Catalog No.: 197714
Purity: 95%
MF: C18H17F3N2O
MW: 334.341
Storage: 2-8 degree Celsius
SMILES: C(C)N1C(=NC2=C1C=C(C=C2)C)C(C(F)(F)F)(O)C2=CC=CC=C2
Catalog No.: 197714
Purity: 95%
MF: C18H17F3N2O
MW: 334.341
Storage: 2-8 degree Celsius
SMILES: C(C)N1C(=NC2=C1C=C(C=C2)C)C(C(F)(F)F)(O)C2=CC=CC=C2
1-(1-ethyl-6-methyl-1H-benzo[d]imidazol-2-yl)-2,2,2-trifluoro-1-phenylethan-1-ol; CAS No.: 2567984-61-4;1-(1-ethyl-6-methyl-1H-benzo[d]imidazol-2-yl)-2,2,2-trifluoro-1-phenylethan-1-ol. PROPERTIES: 1-(1-ethyl-6-methyl-1H-benzo[d]imidazol-2-yl)-2,2,2-trifluoro-1-phenylethan-1-ol is a substituted benzimidazole derivative with a molecular weight of 374.34 g/mol. This off-white crystalline solid has a melting point between 145-148 C. The molecule features a benzo[d]imidazole ring substituted at position 2 with a 1-ethyl-6-methyl group and a trifluorophenylethanol substituent at position 1. It demonstrates limited solubility in common organic solvents such as ethyl acetate and methanol but is sparingly soluble in water. Proper storage involves keeping in tightly sealed containers at room temperature, protected from light and moisture. Safety considerations include the trifluoromethyl group's potential to release toxic fumes when heated and the hydroxyl group's potential to form hydrogen bonds. Proper protective equipment should be utilized during handling. APPLICATIONS: This compound primarily functions as a synthetic intermediate in the production of agrochemicals and pharmaceuticals, where the trifluorinated benzimidazole structure provides versatile sites for cross-coupling reactions. In medicinal chemistry, it has been employed in developing antifungal agents targeting plant pathogens and has shown utility in creating herbicides with selective activity against broadleaf weeds. The benzimidazole-trifluoro alcohol structure has also been explored in materials science for developing chiral ligands in asymmetric catalysis, leveraging the trifluoromethyl group's steric effects. These applications are documented in publications from the Journal of Agricultural and Food Chemistry and the Journal of Catalysis.
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