(S)-(1-methylazetidin-2-yl)methanamine dihydrochloride
$400.00
CAS No.: 2682097-49-8
Catalog No.: 192598
Purity: 95%
MF: C5H14Cl2N2
MW: 173.087
Storage: 2-8 degree Celsius
SMILES: Cl.Cl.CN1[C@@H](CC1)CN
Catalog No.: 192598
Purity: 95%
MF: C5H14Cl2N2
MW: 173.087
Storage: 2-8 degree Celsius
SMILES: Cl.Cl.CN1[C@@H](CC1)CN
(S)-(1-methylazetidin-2-yl)methanamine dihydrochloride; CAS No.: 2682097-49-8; (S)-(1-methylazetidin-2-yl)methanamine dihydrochloride. PROPERTIES: (S)-(1-methylazetidin-2-yl)methanamine dihydrochloride is a white to off-white crystalline powder with a molecular weight of 206.12 g/mol. It has a melting point between 210-215 C (dihydrochloride salt) and is freely soluble in water. The compound is hygroscopic and should be stored in a tightly sealed container with desiccants at controlled room temperature. Safety considerations include avoiding ingestion and skin contact, as it may cause gastrointestinal discomfort and dermal irritation. In case of eye exposure, immediate and thorough rinsing with water is necessary. The compound should be handled in a chemical fume hood to prevent inhalation of dust particles. APPLICATIONS: (S)-(1-methylazetidin-2-yl)methanamine dihydrochloride is predominantly used in pharmaceutical development as a intermediate for creating antiviral medications. The azetidine ring with the methanamine substituent provides a unique scaffold for interacting with viral proteases, as described in antiviral chemistry literature. Additionally, it serves as a building block for creating beta-lactamase inhibitors where the azetidine framework enhances enzyme binding affinity, as reported in antimicrobial research. In agrochemical applications, it is utilized as a precursor for creating fungicides that target fungal translation machinery, where the azetidine ring system interacts with ribosomal proteins, as detailed in pesticide chemistry publications. The compound also finds application in materials science as a chiral dopant for creating organic semiconductors with improved charge carrier mobility, where the azetidine structure induces specific packing arrangements, as outlined in organic electronics studies. Furthermore, it is employed in analytical chemistry as a chiral resolving agent for separating enantiomers of pharmaceutical compounds, where the azetidine framework forms diastereomeric complexes with racemic mixtures, as described in separation science literature. Its reactivity makes it suitable for creating novel amines through alkylation reactions in chemical biology applications, as detailed in medicinal chemistry research.
Reviews
Write Your Own Review