4-oxopiperidine-3-carbonitrile
$300.00
CAS No.: 19166-75-7
Catalog No.: 196303
Purity: 95%
MF: C6H8N2O
MW: 124.143
Storage: 2-8 degree Celsius
SMILES: O=C1C(CNCC1)C#N
Catalog No.: 196303
Purity: 95%
MF: C6H8N2O
MW: 124.143
Storage: 2-8 degree Celsius
SMILES: O=C1C(CNCC1)C#N
4-oxopiperidine-3-carbonitrile; CAS No.: 19166-75-7; 4-oxopiperidine-3-carbonitrile. PROPERTIES: This compound features a 4-oxopiperidine-3-carbonitrile structure, combining a piperidine ring with a ketone and nitrile group. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 131.1 g/mol (C6H8N2O). The melting point ranges between 150-155 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 4-Oxopiperidine-3-carbonitrile serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 4-oxopiperidine-3-carbonitrile structure allows for participation in various reactions, including nucleophilic substitution at the nitrile group and reduction of the ketone to secondary alcohol. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The nitrile group can be hydrolyzed to a carboxylic acid or reduced to an amine for further functionalization. This compound also functions as a building block in the synthesis of agrochemicals (though agricultural applications are excluded here). Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel oxopiperidine derivatives based on the 4-oxopiperidine-3-carbonitrile scaffold.
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