(4,6-dimethoxypyrimidin-5-yl)methanamine
$300.00
CAS No.: 1118786-90-5
Catalog No.: 196401
Purity: 95%
MF: C7H11N3O2
MW: 169.184
Storage: 2-8 degree Celsius
SMILES: COC1=NC=NC(=C1CN)OC
Catalog No.: 196401
Purity: 95%
MF: C7H11N3O2
MW: 169.184
Storage: 2-8 degree Celsius
SMILES: COC1=NC=NC(=C1CN)OC
(4,6-dimethoxypyrimidin-5-yl)methanamine; CAS No.: 1118786-90-5; (4,6-dimethoxypyrimidin-5-yl)methanamine. PROPERTIES: This compound features a (4,6-dimethoxypyrimidin-5-yl)methanamine structure, combining dimethoxypyrimidine and a methanamine group. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 183.2 g/mol (C6H10N4O2). The melting point ranges between 110-115 C, and it exhibits moderate solubility in common organic solvents like ethanol, methanol, and DMSO while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: (4,6-Dimethoxypyrimidin-5-yl)methanamine serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its (4,6-dimethoxypyrimidin-5-yl)methanamine structure allows for participation in various reactions, including nucleophilic substitution at the pyrimidine ring and amine bond formation. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The dimethoxypyrimidine group provides steric and electronic effects that influence binding interactions with biological targets. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Medicinal Chemistry journals, focusing on optimizing the (4,6-dimethoxypyrimidin-5-yl)methanamine scaffold for improved biological activity and target engagement.
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