4-(2-(piperidin-1-yl)ethoxy)benzoic acid hydrochloride
$450.00
CAS No.: 84449-80-9
Catalog No.: 196300
Purity: 95%
MF: C14H20ClNO3
MW: 285.771
Storage: 2-8 degree Celsius
SMILES: Cl.N1(CCCCC1)CCOC1=CC=C(C(=O)O)C=C1
Catalog No.: 196300
Purity: 95%
MF: C14H20ClNO3
MW: 285.771
Storage: 2-8 degree Celsius
SMILES: Cl.N1(CCCCC1)CCOC1=CC=C(C(=O)O)C=C1
4-(2-(piperidin-1-yl)ethoxy)benzoic acid hydrochloride; CAS No.: 84449-80-9; 4-(2-(piperidin-1-yl)ethoxy)benzoic acid hydrochloride. PROPERTIES: This compound features a 4-(2-(piperidin-1-yl)ethoxy)benzoic acid hydrochloride structure, combining a piperidine group, an ethoxy substituent, and a benzoic acid group, and presented as a hydrochloride salt. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 261.2 g/mol (C14H18ClN2O3). The melting point ranges between 150-155 C, and it exhibits good solubility in water and common organic solvents like ethanol and methanol. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 4-(2-(Piperidin-1-yl)ethoxy)benzoic acid hydrochloride serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 4-(2-(piperidin-1-yl)ethoxy)benzoic acid hydrochloride structure allows for participation in various reactions, including esterification, amide bond formation, and nucleophilic substitution at the piperidine nitrogen. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The piperidine group provides hydrogen-bonding capabilities for improved target binding. This compound also functions as a building block in the synthesis of fluorescent probes and bioconjugation reagents. Academic studies employ it as a model compound in Medicinal Chemistry journals, focusing on optimizing the 4-(2-(piperidin-1-yl)ethoxy)benzoic acid hydrochloride scaffold for improved biological activity and target engagement.
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