3-amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile
$500.00
CAS No.: 122799-98-8
Catalog No.: 196349
Purity: 95%
MF: C9H12N4
MW: 176.223
Storage: 2-8 degree Celsius
SMILES: NC1=NN(C=C1C#N)C1CCCC1
Catalog No.: 196349
Purity: 95%
MF: C9H12N4
MW: 176.223
Storage: 2-8 degree Celsius
SMILES: NC1=NN(C=C1C#N)C1CCCC1
3-amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile; CAS No.: 122799-98-8; 3-amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile. PROPERTIES: This compound features a 3-amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile structure, combining an amino group, a cyclopentyl substituent, and a pyrazole carbonitrile framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 191.2 g/mol (C9H11N5). The melting point ranges between 140-145 C, and it exhibits moderate solubility in common organic solvents like ethanol, methanol, and DMSO while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 3-Amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 3-amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile structure allows for participation in various reactions, including nucleophilic substitution at the pyrazole ring and hydrogen bonding interactions through the amino group. In medicinal chemistry, it is used to develop bioactive molecules targeting kinases, proteases, and G protein-coupled receptors. The cyclopentyl group provides steric protection and metabolic stability. This compound also functions as a building block in the synthesis of fluorescent dyes and bioconjugation reagents. Academic studies employ it as a model compound in Medicinal Chemistry journals, focusing on optimizing the 3-amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile scaffold for improved biological activity and pharmacokinetic properties.
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