8-(trifluoromethoxy)quinoline-3-carboxylic acid
$360.00
CAS No.: 2002472-85-5
Catalog No.: 192185
Purity: 95%
MF: C11H6F3NO3
MW: 257.167
Storage: 2-8 degree Celsius
SMILES: FC(OC=1C=CC=C2C=C(C=NC12)C(=O)O)(F)F
Catalog No.: 192185
Purity: 95%
MF: C11H6F3NO3
MW: 257.167
Storage: 2-8 degree Celsius
SMILES: FC(OC=1C=CC=C2C=C(C=NC12)C(=O)O)(F)F
8-(trifluoromethoxy)quinoline-3-carboxylic acid; CAS No.: 2002472-85-5; 8-(trifluoromethoxy)quinoline-3-carboxylic acid. PROPERTIES: 8-(trifluoromethoxy)quinoline-3-carboxylic acid is a white to off-white crystalline powder with molecular formula C10H5F3N2O2. It has a melting point in the range of 210-215 C and exhibits low aqueous solubility but good solubility in common organic solvents. Proper storage conditions include maintaining in a tightly sealed container at 2-8 C to preserve stability. Safety measures necessitate protective eyewear, gloves, and avoiding release to the environment as this compound may pose ecological hazards. APPLICATIONS: This multifunctional compound is extensively used in the pharmaceutical industry as a synthon for creating bioactive molecules. Its trifluoromethoxy substitution pattern enhances lipophilicity, making it suitable for developing CNS-targeted drugs. According to pharmaceutical patents, 8-(trifluoromethoxy)quinoline-3-carboxylic acid derivatives have shown activity against various cancer cell lines. Additionally, the compound serves as a precursor in the synthesis of fluorescent probes for cellular imaging applications as reported in biochemical research journals.
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