5-fluoro-2-(trifluoromethoxy)nitrobenzene
$300.00
CAS No.: 123572-62-3
Catalog No.: 194093
Purity: 95%
MF: C7H3F4NO3
MW: 225.097
Storage: 2-8 degree Celsius
SMILES: FC=1C=CC(=C(C1)[N+](=O)[O-])OC(F)(F)F
Catalog No.: 194093
Purity: 95%
MF: C7H3F4NO3
MW: 225.097
Storage: 2-8 degree Celsius
SMILES: FC=1C=CC(=C(C1)[N+](=O)[O-])OC(F)(F)F
5-fluoro-2-(trifluoromethoxy)nitrobenzene; CAS No.: 123572-62-3; 5-fluoro-2-(trifluoromethoxy)nitrobenzene. PROPERTIES: 5-fluoro-2-(trifluoromethoxy)nitrobenzene is a crystalline solid. Its molecular formula is C7H3F4NO3, and the molecular weight is approximately 227.10 g/mol. The compound has a melting point of approximately 30-32 C. It is moderately soluble in common organic solvents such as acetone and ethyl acetate, but is poorly soluble in water. For stable storage, it should be kept in a tightly sealed container at 2-8 C, protected from light and moisture. As a nitro compound containing fluorine atoms, it may exhibit certain oxidizing properties and toxicity. When handling it, protective gloves, eye protection, and a lab coat should be worn. In case of skin contact, washing with soap and water is necessary, and in case of eye contact, thorough rinsing with water is required. APPLICATIONS: In organic synthesis, 5-fluoro-2-(trifluoromethoxy)nitrobenzene serves as a versatile intermediate. The nitro group can be reduced to an amine group, and the trifluoromethoxy group provides unique electronic effects that can influence the reactivity of the aromatic ring. The fluorine atoms further enhance the compound's reactivity and selectivity. In the pharmaceutical industry, derivatives of 5-fluoro-2-(trifluoromethoxy)nitrobenzene can be explored as potential drug candidates. For instance, in the development of certain antimalarial drugs, the structure of this compound can be modified to enhance the drug's efficacy against malaria parasites (as reported in medicinal chemistry journals). Furthermore, in the field of chemical research, it can be used as a starting material for the synthesis of novel organic compounds with potential applications in materials science and catalysis (as mentioned in organic chemistry research papers).
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