3-bromo-5-(trifluoromethoxy)benzoyl chloride
$150.00
CAS No.: 1092461-36-3
Catalog No.: WLZ1705
Purity: 95%
MF: C8H3BrClF3O2
MW: 303.461
Storage: 2-8 degree Celsius
SMILES: BrC=1C=C(C(=O)Cl)C=C(C1)OC(F)(F)F
Catalog No.: WLZ1705
Purity: 95%
MF: C8H3BrClF3O2
MW: 303.461
Storage: 2-8 degree Celsius
SMILES: BrC=1C=C(C(=O)Cl)C=C(C1)OC(F)(F)F
CAS NO.: 1092461-36-3; 3-bromo-5-(trifluoromethoxy)benzoyl chloride. PROPERTIES: This halogenated aromatic acyl chloride features a bromine atom and a trifluoromethoxy group on a benzene ring connected to an acyl chloride group, creating a molecule with potential applications in organic synthesis and pharmaceutical research. The 3-bromo-5-(trifluoromethoxy)benzoyl chloride typically appears as a white to off-white crystalline solid with moderate solubility in common organic solvents. Its molecular structure includes electron-withdrawing trifluoromethoxy and bromine groups that influence the electronic properties of the aromatic system. For optimal stability and to prevent premature reactions, this compound should be stored at 2-8 degree Celsius in an amber glass bottle under an inert atmosphere. When handling, appropriate safety measures including nitrile gloves and safety goggles are recommended. This compound is sensitive to light and moisture, requiring careful environmental control during storage and use. In case of skin contact, wash thoroughly with soap and water; if eye contact occurs, rinse immediately and seek medical evaluation. APPLICATIONS: The 3-bromo-5-(trifluoromethoxy)benzoyl chloride serves as a versatile building block in organic synthesis, particularly for creating acylated bioactive molecules. The acyl chloride group provides a handle for nucleophilic acyl substitution reactions, enabling the creation of amides, esters, and other derivatives. In medicinal chemistry, this compound functions as an intermediate for developing pharmaceuticals targeting enzyme inhibitors and receptor modulators. The trifluoromethoxy and bromine substituents contribute to target binding affinity and selectivity. Additionally, the molecule finds utility in materials science as a monomer for creating polymers with specific electronic and optical properties. Researchers utilizing this compound can benefit from its functional group versatility, enabling the development of diverse molecular architectures for applications ranging from drug discovery to advanced materials.
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