3-(difluoromethoxy)aniline
$300.00
CAS No.: 22236-08-4
Catalog No.: 196683
Purity: 95%
MF: C7H7F2NO
MW: 159.135
Storage: 2-8 degree Celsius
SMILES: FC(OC=1C=C(N)C=CC1)F
Catalog No.: 196683
Purity: 95%
MF: C7H7F2NO
MW: 159.135
Storage: 2-8 degree Celsius
SMILES: FC(OC=1C=C(N)C=CC1)F
3-(difluoromethoxy)aniline; CAS No.: 22236-08-4; 3-(difluoromethoxy)aniline. PROPERTIES: This difluoromethoxy-substituted aniline features molecular formula C?H?F?NO with molecular weight 159.13 g/mol. Exists as a liquid. Soluble in polar aprotic solvents like ethyl acetate and dichloromethane. Boiling point approximately 140-145 C. Exhibits IR absorption for amine groups. Thermogravimetric analysis shows decomposition above 180 C under nitrogen. Store at 2-8 C in sealed containers. May cause skin irritation and eye damage. APPLICATIONS: As a difluoromethoxy-substituted aniline, 3-(difluoromethoxy)aniline is used in sulfa drug synthesis. The amine group undergoes diazotization and coupling reactions to form bioactive azo derivatives. Also used in fluorescent probe synthesis, enabling conjugation via reductive amination. In materials science, it enhances thermal stability in polyurethane foams due to difluoromethoxy substituents.
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