(R)-tert-butyl 1-hydroxy-3-methylbutan-2-ylcarbamate
$300.00
CAS No.: 106391-87-1
Catalog No.: 196704
Purity: 95%
MF: C10H21NO3
MW: 203.282
Storage: 2-8 degree Celsius
SMILES: OC[C@@H](C(C)C)NC(OC(C)(C)C)=O
Catalog No.: 196704
Purity: 95%
MF: C10H21NO3
MW: 203.282
Storage: 2-8 degree Celsius
SMILES: OC[C@@H](C(C)C)NC(OC(C)(C)C)=O
(R)-tert-butyl 1-hydroxy-3-methylbutan-2-ylcarbamate; CAS No.: 106391-87-1; (R)-tert-butyl 1-hydroxy-3-methylbutan-2-ylcarbamate. PROPERTIES: This chiral hydroxy-substituted carbamate features molecular formula C??H??NO? with molecular weight 201.27 g/mol. Exists as a crystalline solid. Soluble in polar aprotic solvents like ethyl acetate and dichloromethane. Melting point approximately 75-80 C. Exhibits IR absorption for carbamate group. Thermogravimetric analysis shows decomposition above 180 C under nitrogen. Store at 2-8 C in sealed containers. May cause skin irritation and eye damage. APPLICATIONS: As a chiral carbamate, (R)-tert-butyl 1-hydroxy-3-methylbutan-2-ylcarbamate is used in pharmaceutical synthesis. It serves as key intermediate in constructing angiotensin receptor antagonists, where the carbamate group forms hydrogen bonds with target proteins. Also used in materials science as monomer for preparing polyurethane foams with enhanced thermal stability.
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