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(R)-3-aminopropane-1,2-diol; CAS No.: 66211-46-9; (R)-3-aminopropane-1,2-diol. PROPERTIES: This chiral amino-substituted propanediol features molecular formula C?H?NO? with molecular weight 101.11 g/mol. Exists as a liquid. Soluble in polar protic solvents like methanol and water. Boiling point approximately 130-135 C. Exhibits IR absorption for amine and hydroxyl groups. Thermogravimetric analysis indicates decomposition above 150 C under nitrogen. Store at 2-8 C in sealed containers. May cause skin irritation and eye damage. APPLICATIONS: As a chiral amine, (R)-3-aminopropane-1,2-diol is used in sulfa drug synthesis. The amine group undergoes diazotization and coupling reactions to form bioactive azo derivatives. Also used in fluorescent probe synthesis, enabling conjugation via reductive amination. In materials science, it enhances thermal stability in polyurethane foams due to amino and hydroxyl substituents.