(R)-4-((tert-butoxycarbonyl)amino)-3-hydroxybutanoic acid
$350.00
CAS No.: 120021-39-8
Catalog No.: 197213
Purity: 95%
MF: C9H17NO5
MW: 219.237
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)OC(=O)NC[C@@H](CC(=O)O)O
Catalog No.: 197213
Purity: 95%
MF: C9H17NO5
MW: 219.237
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)OC(=O)NC[C@@H](CC(=O)O)O
(R)-4-((tert-butoxycarbonyl)amino)-3-hydroxybutanoic acid; CAS No.: 120021-39-8; (R)-4-((tert-butoxycarbonyl)amino)-3-hydroxybutanoic acid. PROPERTIES: This chiral hydroxy-substituted amino acid features molecular formula C??H??NO? with molecular weight 227.25 g/mol. It generally appears as a white crystalline powder. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 110-115 C. Exhibits IR absorption for carboxylic acid (~2900-2500 cm??) and hydroxyl groups (~3300 cm??). Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a chiral hydroxy-substituted amino acid, (R)-4-((tert-butoxycarbonyl)amino)-3-hydroxybutanoic acid is predominantly utilized in the synthesis of peptide-based therapeutics. It serves as a key building block for constructing bioactive peptides with enhanced conformational stability, particularly in the development of enzyme inhibitors targeting proteases (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its carboxylic acid functionality enables conjugation to biomolecules via amide bond formation (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyamino acid hydrogels with tunable mechanical properties, where the chiral center influences gelation behavior and biocompatibility (Biomacromolecules).
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