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methyl (R)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride; CAS No.: 919792-96-4; methyl (R)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride. PROPERTIES: This chiral amino-substituted propanoate features molecular formula C??H??NO? with molecular weight 215.25 g/mol. It generally appears as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 130-135 C. Exhibits IR absorption for amide (~1650 cm??) and ester groups (~1750 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a chiral amino-substituted propanoate, methyl (R)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride is predominantly utilized in the synthesis of peptide-based therapeutics. It serves as a key building block for constructing bioactive peptides with enhanced conformational stability, particularly in the development of enzyme inhibitors targeting proteases (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its ester functionality enables conjugation to biomolecules via enzymatic hydrolysis (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyamino acid hydrogels with tunable mechanical properties, where the chiral center influences gelation behavior and biocompatibility (Biomacromolecules).