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dimethyl 2-aminomalonate hydrochloride; CAS No.: 16115-80-3; dimethyl 2-aminomalonate hydrochloride. PROPERTIES: This amino-substituted malonate features molecular formula C?H??ClNO? with molecular weight 177.62 g/mol. Exists as a crystalline solid. Soluble in polar protic solvents like methanol and water. Melting point approximately 100-105 C. Exhibits IR absorption for ester and amine groups. Thermogravimetric analysis shows decomposition above 180 C under nitrogen. Store at 2-8 C in sealed containers. May cause skin irritation and eye damage. APPLICATIONS: As a malonate derivative, dimethyl 2-aminomalonate hydrochloride is used in peptide synthesis. It serves as key intermediate in constructing beta-alanine-containing peptides, where the malonate group forms amide bonds. Also used in materials science as monomer for preparing polyurethane foams with enhanced thermal stability.