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3-aminopropylphosphonic acid; CAS No.: 13138-33-5; 3-aminopropylphosphonic acid. PROPERTIES: This amino-substituted phosphonic acid features molecular formula C?H?NO?P with molecular weight 134.09 g/mol. Exists as a crystalline solid. Soluble in polar protic solvents like methanol and water. Melting point approximately 100-105 C. Exhibits IR absorption for amine and phosphonic acid groups. Thermogravimetric analysis shows decomposition above 180 C under nitrogen. Store at 2-8 C in sealed containers. May cause skin irritation and eye damage. APPLICATIONS: As a phosphonic acid derivative, 3-aminopropylphosphonic acid is used in bone-targeting drug synthesis. It serves as key intermediate in constructing bisphosphonates, where the phosphonic acid group binds to hydroxyapatite in bone tissue. Also used in materials science as monomer for preparing phosphonate-containing polymers with enhanced thermal stability.