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4-amino-3-hydroxybutanoic acid; CAS No.: 924-49-2; 4-amino-3-hydroxybutanoic acid. PROPERTIES: This amino-substituted hydroxy acid features molecular formula C?H?NO? with molecular weight 119.12 g/mol. Exists as a crystalline solid. Soluble in polar protic solvents like methanol and water. Melting point approximately 120-125 C. Exhibits IR absorption for carboxylic acid and hydroxyl groups. Thermogravimetric analysis shows decomposition above 180 C under nitrogen. Store at 2-8 C in sealed containers. May cause skin irritation and eye damage. APPLICATIONS: As a hydroxy acid derivative, 4-amino-3-hydroxybutanoic acid is used in renin inhibitor synthesis. It serves as key intermediate in constructing the transition state analog portion of these inhibitors, where the hydroxy acid group mimics the tetrahedral intermediate formed during substrate cleavage. Also used in materials science as monomer for preparing polyhydroxy acids with enhanced thermal stability.