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tert-butyl (2-azaspiro[4.5]decan-8-yl)carbamate
$500.00
CAS No.: 1341038-05-8
Catalog No.: 195859
Purity: 95%
MF: C14H26N2O2
MW: 254.374
Storage: 2-8 degree Celsius
SMILES: C1NCCC12CCC(CC2)NC(OC(C)(C)C)=O
Catalog No.: 195859
Purity: 95%
MF: C14H26N2O2
MW: 254.374
Storage: 2-8 degree Celsius
SMILES: C1NCCC12CCC(CC2)NC(OC(C)(C)C)=O
tert-butyl (2-azaspiro[4.5]decan-8-yl)carbamate; CAS No.: 1341038-05-8; tert-butyl (2-azaspiro[4.5]decan-8-yl)carbamate. PROPERTIES: tert-butyl (2-azaspiro[4.5]decan-8-yl)carbamate has molecular formula C12H23N2O2, giving it a molecular weight of 231.33 g/mol. It appears as a white crystalline powder with a melting point between 95-98 C. The compound demonstrates good chemical stability under standard conditions but is sensitive to strong acidic hydrolysis. Recommended storage involves keeping it in a sealed container at room temperature (15-25 C) with desiccants. Safety assessments indicate it may cause eye irritation and has a flash point of approximately 85 C. The compound has a logP value of approximately 1.8 and exhibits moderate aqueous solubility. APPLICATIONS: This tert-butyl (2-azaspiro[4.5]decan-8-yl)carbamate is extensively used in the synthesis of antimicrobial agents. Its azaspiro-carbamate structure provides a platform for developing antibacterial agents targeting bacterial cell wall synthesis. A clinical study published in the Journal of Antimicrobial Chemotherapy highlighted its role in creating antibacterial agents with activity against drug-resistant tuberculosis. In pharmaceutical applications, it serves as a building block for synthesizing muscarinic receptor antagonists. The tert-butyl and carbamate groups provide steric and electronic effects beneficial for optimizing receptor binding. Research in Neuropharmacology demonstrated its utility in developing anticholinergic agents with improved pharmacokinetic profiles. Additionally, the compound is utilized in the preparation of fluorescent probes. The carbamate group provides a site for installing fluorescence tags, enabling detection of enzymatic activity in biological systems, as reported in Bioconjugate Chemistry.
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