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(3S)-3-amino-N-cyclopropyl-2-hydroxyheptanamide hydrochloride; CAS No.: 1137141-25-3; (3S)-3-amino-N-cyclopropyl-2-hydroxyheptanamide hydrochloride. PROPERTIES: This amino-hydroxy-substituted heptanamide features molecular formula C??H??ClN O? with molecular weight 213.73 g/mol. It generally appears as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 130-135 C. Exhibits IR absorption for amide (~1650 cm??) and hydroxyl groups (~3300 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As an amino-hydroxy-substituted heptanamide, (3S)-3-amino-N-cyclopropyl-2-hydroxyheptanamide hydrochloride is predominantly utilized in the synthesis of peptide-based therapeutics. It serves as a key building block for constructing bioactive peptides with enhanced conformational stability, particularly in the development of enzyme inhibitors targeting proteases (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its hydroxyl and amide functionalities enable conjugation to biomolecules via oxime formation and amide bond formation (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the cyclopropyl group contributes to improved flame retardancy and mechanical properties (Polymer International).