(1S,3S)-3-aminocyclopentan-1-ol
$300.00
CAS No.: 946593-67-5
Catalog No.: 196768
Purity: 95%
MF: C5H11NO
MW: 101.149
Storage: 2-8 degree Celsius
SMILES: N[C@@H]1C[C@H](CC1)O
Catalog No.: 196768
Purity: 95%
MF: C5H11NO
MW: 101.149
Storage: 2-8 degree Celsius
SMILES: N[C@@H]1C[C@H](CC1)O
(1S,3S)-3-aminocyclopentan-1-ol; CAS No.: 946593-67-5; (1S,3S)-3-aminocyclopentan-1-ol. PROPERTIES: This chiral aminocyclopentanol features molecular formula C?H??NO with molecular weight 101.14 g/mol. It generally appears as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 100-105 C. Exhibits IR absorption for amine (~3300-3000 cm??) and hydroxyl groups (~3300 cm??). Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a chiral aminocyclopentanol, (1S,3S)-3-aminocyclopentan-1-ol is predominantly utilized in the synthesis of kinase inhibitors. It serves as a key intermediate in constructing the core scaffold of these compounds, where the cyclopentyl group provides valuable conformational constraints for selective enzyme inhibition as demonstrated in medicinal chemistry research (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its hydroxyl and amine functionalities enable conjugation to biomolecules via reductive amination and oxime formation (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the cyclopentyl group contributes to improved flame retardancy and mechanical properties (Polymer International).
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