tert-butyl 2-aminocyclohexylcarbamate
$250.00
CAS No.: 317595-54-3
Catalog No.: 196760
Purity: 95%
MF: C11H22N2O2
MW: 214.309
Storage: 2-8 degree Celsius
SMILES: NC1C(CCCC1)NC(OC(C)(C)C)=O
Catalog No.: 196760
Purity: 95%
MF: C11H22N2O2
MW: 214.309
Storage: 2-8 degree Celsius
SMILES: NC1C(CCCC1)NC(OC(C)(C)C)=O
tert-butyl 2-aminocyclohexylcarbamate; CAS No.: 317595-54-3; tert-butyl 2-aminocyclohexylcarbamate. PROPERTIES: This cyclohexyl carbamate features molecular formula C??H??NO? with molecular weight 227.30 g/mol. It generally appears as a white crystalline powder. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 100-105 C. Exhibits IR absorption for amide (~1650 cm??) and carbamate groups (~1700 cm??). Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a cyclohexyl carbamate, tert-butyl 2-aminocyclohexylcarbamate is predominantly utilized in the synthesis of kinase inhibitors. It serves as a key intermediate in constructing the core scaffold of these compounds, where the cyclohexyl group provides valuable conformational constraints for selective enzyme inhibition as demonstrated in medicinal chemistry research (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its carbamate functionality enables conjugation to biomolecules via amide bond formation (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the cyclohexyl group contributes to improved flame retardancy and mechanical properties (Polymer International).
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