trans-3-[(tert-butoxycarbonylamino)methyl]cyclobutanecarboxylicacid
$400.00
CAS No.: 1638772-03-8
Catalog No.: 195563
Purity: 95%
MF: C11H19NO4
MW: 229.276
Storage: 2-8 degree Celsius
SMILES: O=C([C@H]1C[C@H](CNC(OC(C)(C)C)=O)C1)O
Catalog No.: 195563
Purity: 95%
MF: C11H19NO4
MW: 229.276
Storage: 2-8 degree Celsius
SMILES: O=C([C@H]1C[C@H](CNC(OC(C)(C)C)=O)C1)O
trans-3-[(tert-butoxycarbonylamino)methyl]cyclobutanecarboxylicacid; CAS No.: 1638772-03-8; trans-3-[(tert-butoxycarbonylamino)methyl]cyclobutanecarboxylicacid. PROPERTIES: trans-3-[(tert-butoxycarbonylamino)methyl]cyclobutanecarboxylicacid is a white crystalline powder with molecular formula C11H18N2O4. It exhibits a melting point around 185-188 C and moderate thermal stability. The compound shows fair solubility in warm aqueous sodium hydroxide solution and limited solubility in organic solvents. Recommended storage conditions include maintaining temperatures below 25 C in sealed containers. Safety precautions involve using acid-resistant gloves during handling to prevent skin irritation from the carboxylic acid group and ensuring proper waste disposal procedures are followed. APPLICATIONS: This Boc-protected amino acid derivative serves as a valuable intermediate in the synthesis of constrained peptide mimetics, where the trans-3-[(tert-butoxycarbonylamino)methyl]cyclobutanecarboxylicacid group provides conformational restriction conducive to receptor binding (Journal of Medicinal Chemistry). In peptide synthesis, the compound is used as a building block for developing bioactive peptides with enhanced metabolic stability (Bioconjugate Chemistry). Furthermore, its carboxylic acid functionality enables formation of bioactive metal complexes used in photodynamic therapy applications (Photochemistry and Photobiology).
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