![trans-3-[(tert-butoxycarbonylamino)methyl]cyclobutanecarboxylicacid](https://www.chemshuttle.com/media/catalog/product/cache/31dbf0bffbfa69a5826a72cec9a446de/1/9/195563_2.jpg)
3-amino-3-methylcyclobutan-1-one hydrochloride
$300.00
CAS No.: 2089255-22-9
Catalog No.: 195564
Purity: 95%
MF: C5H10ClNO
MW: 135.594
Storage: 2-8 degree Celsius
SMILES: Cl.NC1(CC(C1)=O)C
Catalog No.: 195564
Purity: 95%
MF: C5H10ClNO
MW: 135.594
Storage: 2-8 degree Celsius
SMILES: Cl.NC1(CC(C1)=O)C
3-amino-3-methylcyclobutan-1-one hydrochloride; CAS No.: 2089255-22-9; 3-amino-3-methylcyclobutan-1-one hydrochloride. PROPERTIES: 3-amino-3-methylcyclobutan-1-one hydrochloride appears as a white crystalline powder with molecular formula C5H10ClNO. It exhibits a melting point around 165-168 C and moderate thermal stability. The compound shows good solubility in water and moderate solubility in methanol. Recommended storage requires keeping it in tightly sealed containers at room temperature. Safety considerations involve avoiding skin contact with the hydrochloride salt due to potential irritation and using appropriate eye protection. APPLICATIONS: This amino-substituted cyclobutanone serves as a key intermediate in the synthesis of glucagon-like peptide-1 (GLP-1) receptor agonists for diabetes treatment, where the 3-amino-3-methylcyclobutan-1-one hydrochloride group contributes to receptor binding affinity (Journal of Medicinal Chemistry). In chemical biology, the compound is used as a building block for developing covalent inhibitors targeting protein kinases involved in glucose metabolism pathways (ACS Medicinal Chemistry Letters). Furthermore, its amine functionality enables reductive amination reactions for the preparation of diverse secondary amines used in medicinal chemistry library development (Bioorganic & Medicinal Chemistry Letters).
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