cis-3-methylcyclobutanamine hydrochloride
$300.00
CAS No.: 1093951-55-3
Catalog No.: 196752
Purity: 95%
MF: C5H12ClN
MW: 121.611
Storage: 2-8 degree Celsius
SMILES: Cl.C[C@H]1C[C@H](C1)N
Catalog No.: 196752
Purity: 95%
MF: C5H12ClN
MW: 121.611
Storage: 2-8 degree Celsius
SMILES: Cl.C[C@H]1C[C@H](C1)N
cis-3-methylcyclobutanamine hydrochloride; CAS No.: 1093951-55-3; cis-3-methylcyclobutanamine hydrochloride. PROPERTIES: This methyl-substituted cyclobutanamine features molecular formula C?H??ClN with molecular weight 123.61 g/mol. It typically exists as a white crystalline powder. Soluble in polar protic solvents like methanol and water. Melting point approximately 130-135 C. Exhibits IR absorption for amine (~3300-3000 cm??) and C-H stretches. Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a cyclobutanamine derivative, cis-3-methylcyclobutanamine hydrochloride is predominantly utilized in the synthesis of antipsychotic drugs. It serves as a key intermediate in constructing dopamine receptor antagonists, where the cyclobutane ring provides valuable conformational constraints for selective receptor binding as demonstrated in medicinal chemistry research (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its amine functionality enables conjugation to fluorophores via reductive amination (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the cyclobutane group contributes to improved flame retardancy and mechanical properties (Polymer International).
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