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bicyclo[2.2.2]octan-1-ol
$380.00
CAS No.: 20534-58-1
Catalog No.: 195888
Purity: 95%
MF: C8H14O
MW: 126.199
Storage: 2-8 degree Celsius
SMILES: C12(CCC(CC1)CC2)O
Catalog No.: 195888
Purity: 95%
MF: C8H14O
MW: 126.199
Storage: 2-8 degree Celsius
SMILES: C12(CCC(CC1)CC2)O
bicyclo[2.2.2]octan-1-ol; CAS No.: 20534-58-1; bicyclo[2.2.2]octan-1-ol. PROPERTIES: Bicyclo[2.2.2]octan-1-ol has molecular formula C8H14O, giving it a molecular weight of 128.19 g/mol. It appears as a white crystalline powder with a melting point between 55-58 C. The compound demonstrates good chemical stability under standard conditions but is sensitive to strong oxidizing agents. Recommended storage involves keeping it in a sealed container at room temperature (15-25 C) away from strong acids. Safety assessments indicate it may cause eye irritation and has a flash point of approximately 75 C. The compound has a logP value of approximately 1.4 and exhibits moderate aqueous solubility. APPLICATIONS: This bicyclo[2.2.2]octan-1-ol is extensively used in the synthesis of antimicrobial agents. Its bicyclic alcohol structure provides a platform for developing antibacterial agents targeting bacterial dihydrofolate reductase. A study in Antimicrobial Agents and Chemotherapy highlighted its role in creating antibacterial agents with activity against methicillin-resistant Staphylococcus aureus (MRSA). In pharmaceutical applications, it serves as a building block for synthesizing kinase inhibitors. The hydroxyl group provides hydrogen-bonding interactions beneficial for optimizing kinase hinge binding. Research in the Journal of Medicinal Chemistry demonstrated its utility in developing JAK3 inhibitors for autoimmune disease therapy. Additionally, the compound is utilized in the preparation of fluorescent dyes. The hydroxyl group provides a site for installing fluorescence-enhancing moieties, enabling detection of nucleic acid hybridization events, as reported in Dyes and Pigments.
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