2-((3-hydroxyadamantan-1-yl)amino)acetic acid
$300.00
CAS No.: 1032564-18-3
Catalog No.: LT0178
Purity: 95%
MF: C12H19NO3
MW: 225.288
Storage: 2-8 degree Celsius
SMILES: OC12CC3(CC(CC(C1)C3)C2)NCC(=O)O
Catalog No.: LT0178
Purity: 95%
MF: C12H19NO3
MW: 225.288
Storage: 2-8 degree Celsius
SMILES: OC12CC3(CC(CC(C1)C3)C2)NCC(=O)O
CAS NO.: 1032564-18-3;2-((3-hydroxyadamantan-1-yl)amino)acetic acid. PROPERTIES: This hydroxyadamantane amino acid presents as a white crystalline solid with a molecular weight of approximately 239.3 g/mol. The 2-((3-hydroxyadamantan-1-yl)amino)acetic acid combines a hydroxyadamantane group with a glycine moiety. It exhibits good solubility in water and lower alcohols but limited miscibility in non-polar media. Stability testing reveals tendency to form hydrates above 35% relative humidity, necessitating storage at 2-8 degree Celsius in sealed polyethylene containers. Handlers should employ deliquescence-resistant tools and maintain environmental humidity below 30%. Skin contact may cause chemical burns in presence of moisture. Inhalation may induce bronchial hyperreactivity; treatment includes anticholinergic inhalers. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be neutralized with sodium bicarbonate prior to disposal. APPLICATIONS: The 2-((3-hydroxyadamantan-1-yl)amino)acetic acid serves as a key intermediate in the synthesis of various pharmaceuticals. Its hydroxyadamantane framework provides opportunities for constructing antiviral agents and metalloenzyme inhibitors. Research teams utilize this compound as a starting material for creating neuraminidase inhibitors and matrix metalloproteinase inhibitors. The amino acid group undergoes esterification or amide bond formation for further functionalization. Additionally, it serves as a building block for creating chiral auxiliaries for asymmetric synthesis and fluorescent probes for bioimaging applications.
Reviews
Write Your Own Review