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1-(3-hydroxyadamantan-1-yl)ethanone
$400.00
CAS No.: 39917-38-9
Catalog No.: LT0265
Purity: 95%
MF: C12H18O2
MW: 194.274
Storage: 2-8 degree Celsius
SMILES: OC12CC3(CC(CC(C1)C3)C2)C(C)=O
Catalog No.: LT0265
Purity: 95%
MF: C12H18O2
MW: 194.274
Storage: 2-8 degree Celsius
SMILES: OC12CC3(CC(CC(C1)C3)C2)C(C)=O
CAS NO.: 39917-38-9;1-(3-hydroxyadamantan-1-yl)ethanone. PROPERTIES: This hydroxyadamantane ketone presents as a white crystalline solid with a molecular weight of approximately 217.3 g/mol. The 1-(3-hydroxyadamantan-1-yl)ethanone combines a hydroxyadamantane group with an acetone moiety. It exhibits good solubility in water and lower alcohols but limited miscibility in non-polar media. Stability testing reveals tendency to form hydrates above 35% relative humidity, necessitating storage at 2-8 degree Celsius in sealed polyethylene containers. Handlers should employ deliquescence-resistant tools and maintain environmental humidity below 30%. Skin contact may cause chemical burns in presence of moisture. Inhalation may induce bronchial hyperreactivity; treatment includes anticholinergic inhalers. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be neutralized with sodium bicarbonate prior to disposal. APPLICATIONS: The 1-(3-hydroxyadamantan-1-yl)ethanone serves as a key intermediate in the synthesis of various pharmaceuticals. Its hydroxyadamantane framework provides opportunities for constructing antiviral agents and metalloenzyme inhibitors. Research teams utilize this compound as a starting material for creating neuraminidase inhibitors and matrix metalloproteinase inhibitors. The ketone group undergoes reduction to secondary alcohols for further functionalization. Additionally, it serves as a building block for creating chiral auxiliaries for asymmetric synthesis and fluorescent probes for bioimaging applications.
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