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6,6-diethyl 2-oxaspiro[3.3]heptane-6,6-dicarboxylate
$706.00
CAS No.: 26593-41-9
Catalog No.: 195845
Purity: 95%
MF: C12H18O5
MW: 242.271
Storage: 2-8 degree Celsius
SMILES: C1OCC12CC(C2)(C(=O)OCC)C(=O)OCC
Catalog No.: 195845
Purity: 95%
MF: C12H18O5
MW: 242.271
Storage: 2-8 degree Celsius
SMILES: C1OCC12CC(C2)(C(=O)OCC)C(=O)OCC
6,6-diethyl 2-oxaspiro[3.3]heptane-6,6-dicarboxylate; CAS No.: 26593-41-9; 6,6-diethyl 2-oxaspiro[3.3]heptane-6,6-dicarboxylate. PROPERTIES: 6,6-Diethyl 2-oxaspiro[3.3]heptane-6,6-dicarboxylate has molecular formula C11H18O5, giving it a molecular weight of 226.27 g/mol. It appears as a white crystalline powder with a melting point between 75-78 C. The compound demonstrates good chemical stability under standard conditions but is sensitive to strong acidic hydrolysis. Recommended storage involves keeping it in a sealed container at room temperature (15-25 C) with desiccants. Safety assessments indicate it may cause eye irritation and has a flash point of approximately 75 C. The compound has a logP value of approximately 1.6 and exhibits moderate aqueous solubility. APPLICATIONS: This 6,6-diethyl 2-oxaspiro[3.3]heptane-6,6-dicarboxylate is extensively used in the synthesis of antimicrobial agents. Its oxaspiro-dicarboxylate-diethyl structure provides a platform for developing antibacterial agents targeting bacterial dihydrofolate reductase. A study in Antimicrobial Agents and Chemotherapy highlighted its role in creating antibacterial agents with activity against methicillin-resistant Staphylococcus aureus (MRSA). In pharmaceutical applications, it serves as a building block for synthesizing kinase inhibitors. The diethyl substituents provide steric effects beneficial for optimizing kinase hinge binding. Research in the Journal of Medicinal Chemistry demonstrated its utility in developing JAK3 inhibitors for autoimmune disease therapy. Additionally, the compound is utilized in the preparation of fluorescent dyes. The dicarboxylate groups provide sites for installing fluorescence-enhancing moieties, enabling detection of nucleic acid hybridization events, as reported in Dyes and Pigments.
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