5-fluoro-2-methylbenzyl chloride
$300.00
CAS No.: 22062-55-1
Catalog No.: 194095
Purity: 95%
MF: C8H8ClF
MW: 158.603
Storage: 2-8 degree Celsius
SMILES: FC=1C=CC(=C(CCl)C1)C
Catalog No.: 194095
Purity: 95%
MF: C8H8ClF
MW: 158.603
Storage: 2-8 degree Celsius
SMILES: FC=1C=CC(=C(CCl)C1)C
5-fluoro-2-methylbenzyl chloride; CAS No.: 22062-55-1; 5-fluoro-2-methylbenzyl chloride. PROPERTIES: 5-fluoro-2-methylbenzyl chloride is a colorless liquid. Its molecular formula is C8H8ClF, and the molecular weight is approximately 157.60 g/mol. The compound has a boiling point of approximately 120-122 C at reduced pressure. It is moderately soluble in organic solvents such as dichloromethane and toluene, but is insoluble in water. For proper storage, it should be kept in a sealed container at room temperature, away from moisture and heat. As a benzyl chloride compound, it is highly reactive and can undergo various substitution and coupling reactions. When handling it, protective gloves, eye protection, and a lab coat should be worn. In case of accidental contact with skin or eyes, immediate rinsing with water is necessary. APPLICATIONS: In organic synthesis, 5-fluoro-2-methylbenzyl chloride serves as a valuable alkylating agent. The benzyl chloride group can react with nucleophiles such as amines, alcohols, and thiols to form corresponding alkylated products. The fluorine and methyl groups influence the reactivity and selectivity of the benzyl position. In the chemical industry, it can be used as a raw material for the synthesis of various organic compounds. For example, in the preparation of certain pharmaceutical intermediates, 5-fluoro-2-methylbenzyl chloride can be used to introduce benzyl groups into drug molecules, thereby modifying their biological activities and pharmacokinetic properties (as described in pharmaceutical chemistry literature). Additionally, in the field of materials science, it can be incorporated into the synthesis of specialty polymers or coatings, where its structure can enhance the material's thermal stability and chemical resistance (as noted in polymer materials research papers).
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