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((2R,5R)-5-methylpiperazin-2-yl)methanol hydrochloride
$300.00
CAS No.: 1403898-63-4
Catalog No.: TQP0803
Purity: 95%
MF: C6H15ClN2O
MW: 166.652
Storage: 2-8 degree Celsius
SMILES: Cl.C[C@H]1NC[C@@H](NC1)CO
Catalog No.: TQP0803
Purity: 95%
MF: C6H15ClN2O
MW: 166.652
Storage: 2-8 degree Celsius
SMILES: Cl.C[C@H]1NC[C@@H](NC1)CO
CAS NO.: 1403898-63-4;((2R,5R)-5-methylpiperazin-2-yl)methanol hydrochloride. PROPERTIES: This chiral piperazine methanol salt presents as a white hygroscopic powder with a molecular weight of approximately 171.6 g/mol (free base). The ((2R,5R)-5-methylpiperazin-2-yl)methanol hydrochloride combines a chiral piperazine ring with a hydroxymethyl group. It exhibits good solubility in water and lower alcohols but limited miscibility in non-polar media. Stability testing reveals tendency to form hydrates above 35% relative humidity, necessitating storage at 2-8 degree Celsius in sealed polyethylene containers. Handlers should employ deliquescence-resistant tools and maintain environmental humidity below 30%. Skin contact may cause chemical burns in presence of moisture. Inhalation may induce bronchial hyperreactivity; treatment includes anticholinergic inhalers. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be neutralized with sodium bicarbonate prior to disposal. APPLICATIONS: The ((2R,5R)-5-methylpiperazin-2-yl)methanol hydrochloride serves as a key intermediate in the synthesis of various pharmaceuticals. Its chiral piperazine framework provides opportunities for constructing muscarinic receptor modulators and beta-blockers. Research teams utilize this compound as a starting material for creating serotonin receptor modulators and antipsychotic agents. The hydroxymethyl group enhances water solubility compared to non-hydroxy analogs. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity and fluorescent probes for bioimaging applications.
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