benzyl (R)-3-methylpiperazine-1-carboxylate hydrochloride
$200.00
CAS No.: 1217831-52-1
Catalog No.: 192769
Purity: 95%
MF: C13H19ClN2O2
MW: 270.76
Storage: 2-8 degree Celsius
SMILES: Cl.C[C@@H]1CN(CCN1)C(=O)OCC1=CC=CC=C1
Catalog No.: 192769
Purity: 95%
MF: C13H19ClN2O2
MW: 270.76
Storage: 2-8 degree Celsius
SMILES: Cl.C[C@@H]1CN(CCN1)C(=O)OCC1=CC=CC=C1
benzyl (R)-3-methylpiperazine-1-carboxylate hydrochloride; CAS No.: 1217831-52-1; benzyl (R)-3-methylpiperazine-1-carboxylate hydrochloride. PROPERTIES: This methylated piperazine carbamate salt has molecular formula C12H18N2O2 {HCl. It generally appears as a white crystalline powder. The benzyl (R)-3-methylpiperazine-1-carboxylate hydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in common polar solvents. Its melting point ranges between 160-165 C (with decomposition), and it has a molecular weight of approximately 254.75 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The hydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The benzyl (R)-3-methylpiperazine-1-carboxylate hydrochloride functions as a valuable intermediate in the synthesis of serotonin receptor antagonists for psychiatric disorders where the piperazine ring provides essential hydrogen bonding interactions with receptor subtypes (as detailed in medicinal chemistry literature). The benzyl group enhances metabolic stability by preventing oxidative degradation. Additionally, the compound serves as a building block in the preparation of bioconjugates for drug delivery systems where the carbamate group reacts with targeting moieties, as described in pharmaceutical sciences journals. The carbamate group can be further functionalized through hydrolysis or alkylation reactions to produce various derivatives for chemical research applications.
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