benzyl 4,4-difluoro-3-hydroxypiperidine-1-carboxylate
$300.00
CAS No.: 1334417-91-2
Catalog No.: 172011
Purity: 95%
MF: C13H15F2NO3
MW: 271.263
Storage: 2-8 degree Celsius
SMILES: OC1CN(CCC1(F)F)C(=O)OCC1=CC=CC=C1
Catalog No.: 172011
Purity: 95%
MF: C13H15F2NO3
MW: 271.263
Storage: 2-8 degree Celsius
SMILES: OC1CN(CCC1(F)F)C(=O)OCC1=CC=CC=C1
benzyl 4,4-difluoro-3-hydroxypiperidine-1-carboxylate; CAS No.: 1334417-91-2; ChemShuttle's role as a custom chemical synthesis company is highlighted by benzyl 4,4-difluoro-3-hydroxypiperidine-1-carboxylate. This fluorinated piperidine serves as a key intermediate for PROTAC development. The hydroxyl group enables conjugation to E3 ligase ligands, while the benzyl carbamate allows selective deprotection. Applications include targeted degradation of BET family proteins and kinase scaffolds. The company provides binding affinity data for common E3 ligases, facilitating rational design of ternary complexes. Technical support includes optimization of linker lengths and flexibility for optimal degradation efficiency.
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