1-tert-butyl 3-ethyl 5,5-difluoro-4-hydroxypiperidine-1,3-dicarboxylate
$435.00
CAS No.: 1356338-61-8
Catalog No.: 172016
Purity: 95%
MF: C13H21F2NO5
MW: 309.309
Storage: 2-8 degree Celsius
SMILES: CCOC(=O)C1CN(CC(F)(F)C1O)C(=O)OC(C)(C)C
Catalog No.: 172016
Purity: 95%
MF: C13H21F2NO5
MW: 309.309
Storage: 2-8 degree Celsius
SMILES: CCOC(=O)C1CN(CC(F)(F)C1O)C(=O)OC(C)(C)C
1-tert-butyl 3-ethyl 5,5-difluoro-4-hydroxypiperidine-1,3-dicarboxylate; CAS No.: 1356338-61-8; Operating as a custom synthesis companies member, ChemShuttle supplies 1-tert-butyl 3-ethyl 5,5-difluoro-4-hydroxypiperidine-1,3-dicarboxylate. This fluorinated piperidine serves as a building block for prodrug development targeting phosphatase-mediated activation. The hydroxyl group enables phosphate conjugation, while the difluoro substitution enhances metabolic stability. Applications include nucleotide analog prodrugs and targeted cancer therapies. ChemShuttle provides enzymatic hydrolysis data using alkaline phosphatase isoforms. Technical support includes optimization of protecting group strategies for selective phosphorylation.
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