tert-butyl 2-chloro-5-nitrobenzoate

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4-fluorobenzaldehydeoxime

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benzyl 2-bromoethylcarbamate

$300.00
CAS No.: 53844-02-3
Catalog No.: 193143
Purity: 95%
MF: C10H12BrNO2
MW: 258.115
Storage: 2-8 degree Celsius
SMILES: BrCCNC(OCC1=CC=CC=C1)=O
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benzyl 2-bromoethylcarbamate; CAS No.: 53844-02-3 benzyl 2-bromoethylcarbamate. PROPERTIES: benzyl 2-bromoethylcarbamate is a colorless to pale yellow liquid with a molecular weight of 263.1 g/mol. It has a boiling point around 150-155 C at reduced pressure and a density of approximately 1.3 g/cm?. The compound exhibits typical carbamate reactivity and should be handled with care to prevent hydrolysis. When working with benzyl 2-bromoethylcarbamate, protective equipment including gloves and eye protection should be worn. Storage should be in a tightly sealed container at temperatures below 10 C, preferably under an inert atmosphere to prevent degradation. The compound is sensitive to acidic and basic conditions, which may cause hydrolysis of the carbamate group. APPLICATIONS: benzyl 2-bromoethylcarbamate serves as a protected amine intermediate in the synthesis of pharmaceuticals and advanced materials. Its bromine substituent provides a useful handle for cross-coupling reactions, enabling the preparation of various substituted alkyl systems. Derivatives of this compound have been explored in the development of kinase inhibitors and other targeted therapeutics, as reported in the Journal of Medicinal Chemistry. The benzyl protection provides a convenient handle for further functionalization in synthetic sequences. Additionally, the compound can be utilized in the synthesis of molecular sensors and fluorescent probes, as described in Chemical Communications. The combination of the benzyl and carbamate protections makes this compound particularly useful in solid-phase synthesis and the preparation of combinatorial libraries for drug discovery, as highlighted in the Journal of Combinatorial Chemistry. The brominated alkyl group also makes it suitable for use in organic electronics as a building block for conductive polymers, as noted in Advanced Materials.

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