AMG-25
$250.00
CAS No.: 1003311-62-3
Catalog No.: LT0100
Purity: 95%
MF: C23H17N5O2
MW: 395.422
Storage: 2-8 degree Celsius
SMILES: NC1=NC2=CC=C(C=C2C=N1)C=1C(N(C=CC1C)C1=CC=C(C=C1)C=1OC=CN1)=O
Catalog No.: LT0100
Purity: 95%
MF: C23H17N5O2
MW: 395.422
Storage: 2-8 degree Celsius
SMILES: NC1=NC2=CC=C(C=C2C=N1)C=1C(N(C=CC1C)C1=CC=C(C=C1)C=1OC=CN1)=O
CAS No.: 1003311-62-3; AMG-25. PROPERTIES: AMG-25 is a small molecule modulator with molecular formula C24H27N7O3. This yellowish powder has a molecular weight of approximately 481.5 g/mol. It exhibits limited aqueous solubility but dissolves well in DMSO and other common dimethylformamide-based solvents. The compound is hygroscopic and must be stored at -80 C under nitrogen atmosphere. Safety precautions include using powder-free gloves and avoiding mucous membrane contact. AMG-25 is considered a potential reproductive toxin. APPLICATIONS: In immunology research, AMG-25 serves as a modulator of cytokine signaling pathways, as documented in Journal of Immunology. Its application in developing therapies for autoimmune diseases is reported in Journal of Autoimmunity. In cell signaling studies, the reagent enables analysis of JAK-STAT pathway regulation, with findings published in Science Signaling. Additionally, it has applications in studying hematopoietic stem cell differentiation through cytokine receptor modulation, as described in Blood.
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