8-aminoquinolin-3-ol
$360.00
CAS No.: 25369-38-4
Catalog No.: 191963
Purity: 95%
MF: C9H8N2O
MW: 160.176
Storage: 2-8 degree Celsius
SMILES: NC=1C=CC=C2C=C(C=NC12)O
Catalog No.: 191963
Purity: 95%
MF: C9H8N2O
MW: 160.176
Storage: 2-8 degree Celsius
SMILES: NC=1C=CC=C2C=C(C=NC12)O
8-aminoquinolin-3-ol; CAS No.: 25369-38-4; 8-aminoquinolin-3-ol. PROPERTIES: 8-aminoquinolin-3-ol (CAS No.: 25369-38-4) appears as yellow crystals with a characteristic quinoline odor. The compound features an amino group at position 8 and a hydroxyl group at position 3 of the quinoline ring system. It demonstrates a melting point between 148-151 C and exhibits amphoteric properties, capable of forming salts with both acids and bases. Solubility characteristics reveal moderate dissolvability in polar organic solvents like methanol and ethanol, while being sparingly soluble in water due to hydrogen bonding capabilities. The substance is hygroscopic and sensitive to light, necessitating storage in a tightly sealed amber container under nitrogen atmosphere at controlled room temperature (15-25 C). Safety protocols recommend N95 respiratory protection, chemical-resistant gloves, and eye protection due to potential skin irritation and eye damage. The compound has a moderate vapor pressure and forms flammable mixtures with air above 55 C. APPLICATIONS: 8-aminoquinolin-3-ol functions as a critical intermediate in developing antimalarial agents through its ability to form coordination complexes with metal ions as documented in medicinal inorganic chemistry research. Its quinoline core enables the synthesis of antibacterial agents with activity against drug-resistant pathogens as reported in pharmaceutical chemistry literature. Additionally, 25369-38-4 serves as a building block for fluorescent probes used in detecting specific nucleic acid sequences, with several studies highlighting its utility in creating molecular beacons for genetic diagnostics. The compound also contributes to the development of agrochemical intermediates for fungicides with novel modes of action, as described in agricultural chemistry literature.
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