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7-(methylsulfonyl)quinoline-3-carboxylic acid; CAS No.: 1956341-19-7; 7-(methylsulfonyl)quinoline-3-carboxylic acid. PROPERTIES: 7-(methylsulfonyl)quinoline-3-carboxylic acid is a solid compound with a molecular weight of 263.3 g/mol. It has a melting point ranging from 218 to 221 C (decomposition) and is moderately soluble in hot water and polar organic solvents. The compound is hygroscopic and should be stored in a sealed container with desiccant. It is sensitive to acidic conditions and may undergo hydrolysis in strongly basic environments. When handling, protective eyewear and gloves should be worn, and in case of accidental ingestion, immediate medical attention is required. APPLICATIONS: 7-(methylsulfonyl)quinoline-3-carboxylic acid functions as a building block in the synthesis of pharmaceuticals, particularly in the development of anti-inflammatory and analgesic agents. The carboxylic acid group allows for esterification or amide formation, while the methylsulfonyl group provides additional reactivity. In medicinal chemistry, 7-(methylsulfonyl)quinoline-3-carboxylic acid is employed in the design of compounds targeting specific protein-protein interactions. It also serves as a precursor in the synthesis of quinoline-based dyes with applications in biological staining techniques. Additionally, the compound is used in the preparation of metal complexes for catalytic applications in organic transformations. These applications are typically encountered in pharmaceutical R&D departments and specialized chemical synthesis laboratories.