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7-(methylsulfonyl)quinolin-3-amine; CAS No.: 944401-82-5; 7-(methylsulfonyl)quinolin-3-amine. PROPERTIES: 7-(methylsulfonyl)quinolin-3-amine is a solid compound with a molecular weight of 232.3 g/mol. It has a melting point ranging from 165 to 168 C and is moderately soluble in polar organic solvents such as methanol and acetone. The compound is sensitive to oxidation and should be stored under an inert atmosphere like nitrogen. It is stable under normal laboratory conditions but may decompose upon exposure to strong acids or bases. When handling, protective equipment including gloves and goggles should be worn, and in case of accidental ingestion, immediate medical attention is required. APPLICATIONS: 7-(methylsulfonyl)quinolin-3-amine functions as a valuable intermediate in the synthesis of pharmaceuticals, particularly in the development of anticancer and antiviral agents. The amine group provides a site for further functionalization, while the methylsulfonyl group enhances solubility properties. In medicinal chemistry, 7-(methylsulfonyl)quinolin-3-amine is used to create compounds with improved pharmacokinetic profiles. It also serves as a building block in the synthesis of fluorescent dyes, where its quinoline core contributes to emission characteristics. Additionally, the compound is employed in the preparation of coordination compounds with metal ions for catalytic applications in organic synthesis. These uses are typically encountered in pharmaceutical R&D departments and specialized chemical synthesis laboratories.