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5-(methylsulfonyl)quinolin-3-amine; CAS No.: 1956341-17-5; 5-(methylsulfonyl)quinolin-3-amine. PROPERTIES: 5-(methylsulfonyl)quinolin-3-amine is a crystalline powder with a molecular weight of 232.3 g/mol. It has a melting point between 170 and 173 C and is moderately soluble in hot water and polar organic solvents. The compound is hygroscopic and should be stored in a sealed container with desiccant. It is sensitive to acidic conditions and may undergo hydrolysis in strongly basic environments. When handling, protective eyewear and gloves should be worn, and in case of eye contact, immediate rinsing with water is advised. APPLICATIONS: 5-(methylsulfonyl)quinolin-3-amine serves as a building block in the synthesis of pharmaceuticals, particularly in the development of anti-inflammatory and analgesic agents. The amine group provides a site for further modification, such as acylation or alkylation. In medicinal chemistry, 5-(methylsulfonyl)quinolin-3-amine is employed in the design of compounds targeting specific protein-protein interactions. It also functions as a precursor in the synthesis of quinoline-based dyes with applications in biological staining techniques. Additionally, the compound is used in the preparation of metal complexes for catalytic applications in organic transformations. These applications are commonly found in pharmaceutical research laboratories and chemical manufacturing facilities specializing in heterocyclic compound production.