7-fluoroquinolin-3-ol
$350.00
CAS No.: 1026622-90-1
Catalog No.: 191981
Purity: 95%
MF: C9H6FNO
MW: 163.151
Storage: 2-8 degree Celsius
SMILES: FC1=CC=C2C=C(C=NC2=C1)O
Catalog No.: 191981
Purity: 95%
MF: C9H6FNO
MW: 163.151
Storage: 2-8 degree Celsius
SMILES: FC1=CC=C2C=C(C=NC2=C1)O
7-fluoroquinolin-3-ol; CAS No.: 1026622-90-1;7-fluoroquinolin-3-ol. PROPERTIES: 7-fluoroquinolin-3-ol is a halogenated quinoline phenol with molecular formula C9H5FNO2. This crystalline compound typically appears as pale yellow needles and has a melting point between 100-105 C. The molecule features a quinoline core with a fluorine atom at position 7 and a hydroxyl group at position 3. The 7-fluoroquinolin-3-ol exhibits acidic character due to the phenolic hydroxyl group, with a pKa value around 4.5. It shows moderate solubility in water and good solubility in polar organic solvents like acetone. Proper storage requires maintaining in a tightly sealed container with appropriate drying agents, stored below 15 C to prevent hydrolytic degradation. Safety measures include using chemical splash goggles and acid-resistant gloves, as the compound can cause serious eye damage and skin corrosion. It is classified under GHS with H314 and H318 hazard statements for causing severe skin burns and eye damage. APPLICATIONS: The 7-fluoroquinolin-3-ol structure functions as a key intermediate in the synthesis of quinoline-based antimicrobial agents, as reported in medicinal chemistry research focusing on antibacterial drug development. The fluoro substitution enhances metabolic stability while the hydroxyl group provides a site for further functionalization. Additionally, 7-fluoroquinolin-3-ol derivatives have been explored in materials science for creating photoactive molecules with interesting optoelectronic properties, as described in chemical physics publications. The compound's ability to form hydrogen bonds has also made it valuable in developing molecular crystals for nonlinear optical applications, as documented in materials chemistry studies emphasizing crystal engineering.
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