7-bromo-8-methyl-1,2,3,4-tetrahydroisoquinoline
$500.00
CAS No.: 1784607-39-1
Catalog No.: 195574
Purity: 95%
MF: C10H12BrN
MW: 226.117
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=C2CCNCC2=C1C
Catalog No.: 195574
Purity: 95%
MF: C10H12BrN
MW: 226.117
Storage: 2-8 degree Celsius
SMILES: BrC1=CC=C2CCNCC2=C1C
7-bromo-8-methyl-1,2,3,4-tetrahydroisoquinoline; CAS No.: 1784607-39-1; 7-bromo-8-methyl-1,2,3,4-tetrahydroisoquinoline. PROPERTIES: 7-bromo-8-methyl-1,2,3,4-tetrahydroisoquinoline is a colorless oil with molecular formula C10H12BrN. It demonstrates a boiling point around 130-135 C at 10 mmHg and moderate thermal stability. The compound exhibits good solubility in non-polar organic solvents like hexane and moderate solubility in ethyl acetate. Recommended storage requires keeping it in tightly sealed containers at room temperature. Safety considerations involve using explosion-proof equipment when handling due to potential flammability and employing proper engineering controls to minimize vapor release. APPLICATIONS: This brominated tetrahydroisoquinoline serves as a key intermediate in the synthesis of sigma receptor ligands used in neuroimaging studies, where the 7-bromo-8-methyl-1,2,3,4-tetrahydroisoquinoline group provides optimal receptor binding affinity (Journal of Labelled Compounds & Radiopharmaceuticals). In chemical biology, the compound is used as a building block for developing covalent inhibitors targeting protein kinases involved in neuronal signaling pathways (ACS Chemical Neuroscience). Furthermore, its bromine substituent enables cross-coupling reactions for the synthesis of structurally diverse libraries used in central nervous system drug discovery (Journal of Medicinal Chemistry).
Reviews
Write Your Own Review