6-(trifluoromethoxy)quinoline-3-carboxylic acid
$300.00
CAS No.: 2002471-85-2
Catalog No.: 192203
Purity: 95%
MF: C11H6F3NO3
MW: 257.167
Storage: 2-8 degree Celsius
SMILES: FC(OC=1C=C2C=C(C=NC2=CC1)C(=O)O)(F)F
Catalog No.: 192203
Purity: 95%
MF: C11H6F3NO3
MW: 257.167
Storage: 2-8 degree Celsius
SMILES: FC(OC=1C=C2C=C(C=NC2=CC1)C(=O)O)(F)F
6-(trifluoromethoxy)quinoline-3-carboxylic acid; CAS No.: 2002471-85-2; 6-(trifluoromethoxy)quinoline-3-carboxylic acid. PROPERTIES: 6-(trifluoromethoxy)quinoline-3-carboxylic acid appears as a white to off-white solid with molecular weight 244.16 g/mol. It has a melting point between 200-205 C and shows limited solubility in water but good solubility in common organic solvents. Proper storage involves maintaining in a sealed container at room temperature away from heat sources. Safety considerations include wearing protective gloves and eye protection as this compound may cause skin and eye irritation. APPLICATIONS: This trifluoromethoxy-substituted quinoline carboxylic acid is used in the synthesis of HIV-1 integrase inhibitors. The carboxylic acid group forms critical interactions with the enzyme's active site as described in antiviral research papers. In materials science, 6-(trifluoromethoxy)quinoline-3-carboxylic acid derivatives have found use in creating self-assembled monolayers for surface modification. According to materials chemistry journals, the quinoline core promotes adsorption onto metal surfaces while the trifluoromethoxy group imparts chemical resistance.
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