5-chloro-1,2,3,4-tetrahydroisoquinoline
$300.00
CAS No.: 73075-43-1
Catalog No.: 196252
Purity: 95%
MF: C9H10ClN
MW: 167.639
Storage: 2-8 degree Celsius
SMILES: ClC1=C2CCNCC2=CC=C1
Catalog No.: 196252
Purity: 95%
MF: C9H10ClN
MW: 167.639
Storage: 2-8 degree Celsius
SMILES: ClC1=C2CCNCC2=CC=C1
5-chloro-1,2,3,4-tetrahydroisoquinoline; CAS No.: 73075-43-1; 5-chloro-1,2,3,4-tetrahydroisoquinoline. PROPERTIES: This compound features a 5-chloro-1,2,3,4-tetrahydroisoquinoline structure, combining a chloro substituent and a tetrahydroisoquinoline framework. It typically appears as a white to off-white crystalline solid with a molecular weight of approximately 173.6 g/mol (C9H11ClN). The melting point ranges between 90-95 C, and it exhibits moderate solubility in common organic solvents like ethyl acetate, dichloromethane, and tetrahydrofuran while being sparingly soluble in water. Proper storage requires a tightly sealed container in a cool, dry place. Safety considerations include wearing appropriate PPE. It is classified as a skin and eye irritant (GHS07) with the hazard statement H315-H319. APPLICATIONS: 5-Chloro-1,2,3,4-tetrahydroisoquinoline serves as a versatile intermediate in pharmaceutical and chemical synthesis. Its 5-chloro-1,2,3,4-tetrahydroisoquinoline structure allows for participation in various reactions, including nucleophilic substitution at the chloro position and hydrogenation/dehydrogenation reactions. In medicinal chemistry, it is used to develop bioactive molecules targeting the central nervous system and inflammatory pathways. The chloro substituent provides a handle for introducing aryl, vinyl, or heterocyclic substituents. This compound also functions as a building block in the synthesis of complex carbohydrates and glycosides. Academic studies employ it as a model compound in Organic Chemistry journals, focusing on the development of novel chlorotetrahydroisoquinoline derivatives based on the 5-chloro-1,2,3,4-tetrahydroisoquinoline scaffold.
Reviews
Write Your Own Review