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5-bromo-2-(trifluoromethyl)quinoline; CAS No.: 176722-71-7; 5-bromo-2-(trifluoromethyl)quinoline. PROPERTIES: 5-bromo-2-(trifluoromethyl)quinoline is a light-sensitive compound appearing as a brownish solid. It has a molecular weight of 282.06 g/mol and a melting point between 68-72 C. The compound is sparingly soluble in water but dissolves in polar aprotic solvents. Proper storage requires amber glassware, protection from light, and temperatures below 20 C. Safety precautions include avoiding contact with aqueous solutions and using spark-proof tools due to its flammability and potential to cause skin irritation. APPLICATIONS: This brominated, trifluoromethyl-substituted quinoline is used in the synthesis of antiviral agents. The bromine substituent provides a site for Suzuki coupling reactions as detailed in organic synthesis textbooks. According to virology research, derivatives of 5-bromo-2-(trifluoromethyl)quinoline have demonstrated activity against RNA viruses. Additionally, the compound serves as a building block for creating liquid crystal materials in display technologies. As reported in materials science journals, the rigid quinoline core and electron-withdrawing groups impart favorable mesomorphic properties.