5-bromo-2-fluoronitrobenzene
$200.00
CAS No.: 364-73-8
Catalog No.: 192439
Purity: 95%
MF: C6H3BrFNO2
MW: 219.997
Storage: 2-8 degree Celsius
SMILES: BrC=1C=CC(=C(C1)[N+](=O)[O-])F
Catalog No.: 192439
Purity: 95%
MF: C6H3BrFNO2
MW: 219.997
Storage: 2-8 degree Celsius
SMILES: BrC=1C=CC(=C(C1)[N+](=O)[O-])F
5-bromo-2-fluoronitrobenzene; CAS No.: 364-73-8; 5-bromo-2-fluoronitrobenzene. PROPERTIES: 5-bromo-2-fluoronitrobenzene is a crystalline powder with molecular formula C6H4BrFNO2. It has a melting point of approximately 35-40 C and exhibits limited solubility in common organic solvents. The compound is light-sensitive and should be stored in amber glassware at 2-8 C. Safety precautions include wearing protective clothing due to its potential to cause skin burns and using explosion-proof ventilation due to its explosive nature when exposed to heat. APPLICATIONS: This brominated, fluorinated nitrobenzene is used in the development of anticancer prodrugs. The nitro group serves as a reducible moiety that gets activated in the tumor microenvironment as reported in cancer research literature. In chemical biology, 5-bromo-2-fluoronitrobenzene serves as a building block for creating photoaffinity labels. According to biochemical journals, the nitrobenzene scaffold provides a fluorescent signal while the bromine and fluorine groups enable photoinduced cross-linking with target proteins.
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