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5-(benzyloxy)-2-methylbenzenamine; CAS No.: 19499-88-8; 5-(benzyloxy)-2-methylbenzenamine. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C12H13NO and a molecular weight of 187.24 g/mol. It exhibits a melting point in the range of 48-52 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to oxidation and should be stored under inert atmosphere. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as 5-(benzyloxy)-2-methylbenzenamine may cause skin irritation. The amine group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, 5-(benzyloxy)-2-methylbenzenamine serves as a key intermediate for synthesizing antiviral agents, as documented in pharmaceutical research focusing on nucleoside analogs. Its benzyloxy substituent enables improved solubility in biological systems for enhanced bioavailability. Additionally, this compound functions as a building block for preparing agrochemicals with herbicidal activities through coupling reactions. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The aniline ring system also facilitates coordination with metal ions, making it valuable for creating luminescent materials in materials science applications, as evidenced by inorganic chemistry publications.