4-fluoro-3-methylphenylacetic acid
$180.00
CAS No.: 1000520-92-2
Catalog No.: 194065
Purity: 95%
MF: C9H9FO2
MW: 168.167
Storage: 2-8 degree Celsius
SMILES: FC1=C(C=C(C=C1)CC(=O)O)C
Catalog No.: 194065
Purity: 95%
MF: C9H9FO2
MW: 168.167
Storage: 2-8 degree Celsius
SMILES: FC1=C(C=C(C=C1)CC(=O)O)C
4-fluoro-3-methylphenylacetic acid; CAS No.: 1000520-92-2; 4-fluoro-3-methylphenylacetic acid. PROPERTIES: 4-fluoro-3-methylphenylacetic acid is a crystalline solid with a molecular weight of 187.18 g/mol. It typically exhibits a melting point in the range of 125-128 C and limited water solubility, though it dissolves readily in organic solvents such as methanol, ethanol, and dichloromethane. The compound contains reactive functional groups including a carboxylic acid group, fluorine substituent, and methyl group, which contribute to its chemical versatility. For optimal storage, it should be kept in a tightly sealed container at temperatures below 20 C, preferably under inert atmosphere to prevent potential degradation. Safety considerations include wearing appropriate protective clothing, gloves, and eye/face protection to minimize exposure risk. The compound may cause eye irritation and skin irritation, and in case of accidental ingestion, immediate medical attention is advised. APPLICATIONS: 4-fluoro-3-methylphenylacetic acid serves as a valuable intermediate in the synthesis of various pharmaceuticals, particularly in the development of targeted kinase inhibitors for cancer therapy. Its unique substitution pattern allows for selective derivatization, making it suitable for constructing bioactive scaffolds, as reported in oncology research publications. In materials science, the compound functions as a building block for certain types of liquid crystalline materials and conductive polymers. The presence of the carboxylic acid group provides a convenient handle for further functionalization, enabling the formation of various derivatives such as esters, amides, and acid chlorides. Additionally, it is utilized in the preparation of specialty dyes and pigments, where its structure contributes to desired solubility and stability characteristics. Through chemical modification of the carboxylic acid group, it can be converted into various functionalized derivatives, expanding its application scope in organic synthesis. The fluorine substituent enhances the compound's ability to participate in specific interactions, making it useful in supramolecular chemistry applications.
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