4-cyano-2-fluorobenzyl amine
$250.00
CAS No.: 701264-00-8
Catalog No.: 194058
Purity: 95%
MF: C8H7FN2
MW: 150.156
Storage: 2-8 degree Celsius
SMILES: C(#N)C1=CC(=C(CN)C=C1)F
Catalog No.: 194058
Purity: 95%
MF: C8H7FN2
MW: 150.156
Storage: 2-8 degree Celsius
SMILES: C(#N)C1=CC(=C(CN)C=C1)F
4-cyano-2-fluorobenzyl amine; CAS No.: 701264-00-8; 4-cyano-2-fluorobenzyl amine. PROPERTIES: 4-cyano-2-fluorobenzyl amine is a colorless to pale yellow liquid with a molecular weight of 171.1 g/mol. It has a boiling point around 185-187 C at 760 mmHg and exhibits low water solubility while being miscible with common organic solvents such as dichloromethane, ethyl acetate, and tetrahydrofuran. The compound contains reactive functional groups including an amine group, cyano group, and fluorine substituent, which contribute to its chemical versatility. Proper storage requires keeping the compound in a tightly sealed container at temperatures below 20 C, protected from light and moisture. Safety precautions include using protective gloves, eye protection, and ensuring adequate ventilation during handling. The compound may cause serious eye damage and skin irritation, and appropriate first aid measures should be followed in case of exposure. The amine functionality may render it moderately toxic if ingested, and appropriate handling procedures should be followed. APPLICATIONS: 4-cyano-2-fluorobenzyl amine serves as a valuable intermediate in the synthesis of various pharmaceuticals, particularly in the development of targeted kinase inhibitors for cancer therapy. Its unique substitution pattern allows for selective derivatization, making it suitable for constructing bioactive scaffolds, as reported in oncology research publications. In materials science, the compound functions as a building block for certain types of conductive polymers and electroactive materials. The presence of the amine group provides a site for further functionalization, enabling the introduction of various substituents. Additionally, it is utilized in the preparation of specialty dyes and pigments, where its cyano and fluorine substituents contribute to desired optical properties. The cyano group can be converted into various functional groups such as carboxylic acids or amines, expanding its application scope in organic synthesis. The fluorine substituent enhances the compound's ability to participate in specific interactions, making it useful in supramolecular chemistry applications.
Reviews
Write Your Own Review