4-chloro-3',4'-dimethoxybenzophenone
$300.00
CAS No.: 116412-83-0
Catalog No.: 197077
Purity: 95%
MF: C15H13ClO3
MW: 276.719
Storage: 2-8 degree Celsius
SMILES: ClC1=CC=C(C(=O)C2=CC(=C(C=C2)OC)OC)C=C1
Catalog No.: 197077
Purity: 95%
MF: C15H13ClO3
MW: 276.719
Storage: 2-8 degree Celsius
SMILES: ClC1=CC=C(C(=O)C2=CC(=C(C=C2)OC)OC)C=C1
4-chloro-3',4'-dimethoxybenzophenone; CAS No.: 116412-83-0; 4-chloro-3',4'-dimethoxybenzophenone. PROPERTIES: This chloro-dimethoxy-substituted benzophenone features molecular formula C??H??ClO? with molecular weight 258.69 g/mol. It generally appears as a white crystalline powder. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 120-125 C. Exhibits IR absorption for ketone (~1700 cm??) and hydroxyl groups (~3300 cm??). Thermogravimetric analysis reveals weight loss onset above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause mild skin irritation and serious eye damage; therefore, standard laboratory safety precautions including protective clothing and eye protection are recommended during handling. APPLICATIONS: As a chloro-dimethoxy-substituted benzophenone, 4-chloro-3',4'-dimethoxybenzophenone is predominantly utilized in the synthesis of benzophenone-based UV absorbers. It serves as a key intermediate in constructing the core benzophenone framework of these compounds, where the chloro and methoxy groups provide enhanced UV absorption properties as demonstrated in materials science research (Polymer Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its ketone functionality enables conjugation to biomolecules via oxime formation (Bioconjugate Chemistry). In medicinal chemistry, it functions as a building block for constructing kinase inhibitors, where the benzophenone group provides valuable binding affinity for the kinase hinge region (Journal of Medicinal Chemistry).
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